Aclimostat - CAS 2082752-83-6

Aclimostat (ZGN-1061) is a highly potent inhibitor of the MetAP2 enzyme, demonstrating promising efficacy and safety profiles in preclinical trials. In a mouse model of obesity and insulin resistance, ZGN-1061 shows comparable weight loss efficacy to beloranib and improves metabolic parameters. Additionally, ZGN-1061 induces consistent changes in gene transcription in HepG2 cells, further supporting its positive pharmacological effects.

Others, Aminopeptidase

Metabolism, Others

2082663

C26H42N2O6

478.63

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-20°C

Ice Packs

Small Compound