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Molfinity

ACP-5862 - CAS 2230757-47-6

ACP-5862 - CAS 2230757-47-6

SKU:MF-0004312-01

Regular price $1,383.80 USD
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  • Bioactivity

    ACP-5862 is a major active and pyrrolidine ring-opened metabolite of Acalabrutinib (IC50: 5.0 nM for BTK) . Acalabrutinib is an irreversible and highly selective BTK inhibitor (IC50: 3 nM; EC50: 8 nM) .

  • Target

    BTK, Drug Metabolite, Cytochromes P450

  • Related Pathways

    Tyrosine Kinase/Adaptors, Metabolism, Angiogenesis

  • CAS Number

    2230704

  • Molecular Formula

    C26H23N7O3

  • Molecular Weight

    481.51

  • SMILES

    CC#CC(=O)NCCCC(=O)c1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2c(N)nccn12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound