ACTH (6-24) (human) - CAS 33512-65-1

Adrenocorticotropic hormone (6-24) (ACTH (6-24) (human) ) is a fragment of ACTH that acts as a competitive inhibitor of steroidogenesis prompted by full-length ACTH (1-39) and the shortened ACTH (5-24), with dissociation constants (Kd) of 13.4 nM and 3.4 nM, respectively. It also impedes the production of corticosterone and the accumulation of cyclic AMP (cAMP) triggered by human parathyroid hormone (hPTH 1-34) [1] [2].

Glucocorticoid Receptor

Endocrinology/Hormones

33512-65-1

C111H175N35O21

2335.8

C([C@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)N)=O)=O)CCCNC(=N)N)=O)C(NCC(N[C@H](C(=O)N3[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N5[C@H](C(O)=O)CCC5)CC6=CC=C(O)C=C6)=O)C(C)C)=O)CCCCN)=O)[C@@H](C)C)=O)CCC4)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)=O)C(C)C)=O)CCC3)CCCCN)=O)=O)C=7C=8C(NC7)=CC=CC8

-20°C

Ice Packs

Peptide