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Molfinity

AD16 - CAS 311315-04-5

AD16 - CAS 311315-04-5

MF-0061967-01

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Product Details

  • Bioactivity

    AD16 (Acetamide) acts as an inhibitor of LINE-1 retrotransposon endonuclease, exhibiting an IC50 value of 4.7 μM. It decreases LINE-1 retrotransposition in senescent cells and mitigates the resulting DNA damage and inflammation.

  • Target

    Endonuclease

  • Related Pathways

    Cell Cycle/Checkpoint

  • CAS Number

    311315-04-5

  • Molecular Formula

    C24H20N14O3S2

  • Molecular Weight

    616.64

  • SMILES

    O=C(NC1=CC=C2OC(=NC2=C1)C3=CC=C(C=C3)CC(=O)CSC4=NN=C5N4N=CN5N)CSC6=NN=C7N6N=CN7N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound