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Molfinity

Adagrasib - CAS 2326521-71-3

Adagrasib - CAS 2326521-71-3

MF-0017516-01

$54.10 USD
$54.10 USD
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Product Details

  • Bioactivity

    Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib exhibits inhibitory activity against KRAS G12C mutant tumors.

  • Target

    Kras, Ras

  • Related Pathways

    MAPK, GPCR/G Protein

  • CAS Number

    2326447

  • Purity

    0.999

  • Molecular Formula

    C32H35ClFN7O2

  • Molecular Weight

    604.12

  • SMILES

    CN1CCC[C@H]1COc1nc2CN(CCc2c(n1)N1CCN([C@@H](CC#N)C1)C(=O)C(F)=C)c1cccc2cccc(Cl)c12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound