Adezmapimod - CAS 152121-47-6

Adezmapimod (SB 203580) is a selective, ATP-competitive p38 MAPK inhibitor (IC50=0.3-0.5 μM) that activates autophagy and mitochondrial autophagy, with more than 100-fold higher selectivity over PKB, LCK, and GSK-3β.

HSP, p38 MAPK, Mitophagy, Autophagy

Cytoskeletal Signaling, Metabolism, Autophagy, MAPK

152068

0.9993

C21H16FN3OS

377.43

FC1=CC=C(C2=C(N=C(N2)C3=CC=C(S(C)=O)C=C3)C=4C=CN=CC4)C=C1

-20°C

Ice Packs

Small Compound