ADH-1 trifluoroacetate - CAS 1135237-88-5

ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis.

Cadherin

Cytoskeletal Signaling

1135144

0.9998

C24H35F3N8O8S2

684.71

OC(=O)C(F)(F)F.CC(C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(N)=O)NC(C)=O

-20°C

Ice Packs

Peptide