Aditoprime - CAS 56066-63-8

Aditoprime (Aditoprim) is a selective inhibitor of bacterial dihydrofolate reductase (DHFR) that inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime shows good antibacterial activity and broad antimicrobial spectrum, and moreover, excellent pharmacokinetics. Aditoprime inhibits L.casei and E.coli DHFR with IC 50 of 520 and 47 nM, respectively [1] [2] [3].

Others, Antifolate, Antibacterial

Cell Cycle/Checkpoint, Others, Microbiology/Virology

55995

0.9989

C15H21N5O2

303.36

N(C)(C)C1=C(OC)C=C(CC=2C(N)=NC(N)=NC2)C=C1OC

-20°C

Ice Packs

Small Compound