Adonixanthin - CAS 4418-73-9

Adonixanthin ((3S,3'R) -Adonixanthin) is a carotenoid that acts as an orally active antioxidant and anticancer agent. It demonstrates the ability to inhibit the proliferation and migration of glioblastoma cells and provides cellular protection against various injuries, suppressing increased reactive oxygen species (ROS) production. Adonixanthin safeguards cells from photo-induced damage through antioxidative responses and Nrf2 activation. It can halt glioblastoma progression and improve blood-brain barrier permeability in autologous intracerebral hemorrhage (ICH) models. This compound is applicable in research related to glioblastoma (GBM) and intracerebral hemorrhage (ICH) .

Nrf2, ROS, p38 MAPK, NADPH, Akt, ERK, MMP

Metabolism, Proteases/Proteasome, MAPK, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Immunology/Inflammation

4418-73-9

C40H54O3

582.86

C(=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C=1C(C)(C)C[C@H](O)CC1C)\C)\C)/C)/C)\C=2C(C)(C)C[C@H](O)C(=O)C2C

-20°C

Ice Packs

Natural Product