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Molfinity

Adriforant - CAS 943057-12-3

Adriforant - CAS 943057-12-3

MF-0064744-01

$307.11 USD
$307.11 USD
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Product Details

  • Bioactivity

    Adriforant (PF-3893787, ZPL-3893797) is a competitive H4 (histamine receptor 4) antagonist that antagonizes histamine-induced phosphorylation of ERK, normalizes histamine-induced transcriptional changes in mast cells and reduces histamine-dependent Ca2+ fluxes in neurons, which alleviates itching and skin inflammation in mice

  • Target

    Histamine Receptor

  • Related Pathways

    Neuroscience, Immunology/Inflammation, GPCR/G Protein

  • CAS Number

    943042

  • Purity

    0.9984

  • Molecular Formula

    C13H22N6

  • Molecular Weight

    262.35

  • SMILES

    N(C)[C@H]1CN(CC1)C=2C=C(NCC3CC3)N=C(N)N2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound