ADU-S100 - CAS 1638241-89-0

ADU-S100 (MIW815) is a cyclic dinucleotide (CDN) class STING agonist that significantly induces the production of IFN-β and pro-inflammatory cytokines TNF-α, IL-6, and MCP-1, induces TBK1 and IRF3 phosphorylation, and exhibits antitumour activity.

COX, IκB/IKK, IL Receptor, Others, STING, TNF

NF-κB, Apoptosis, Immunology/Inflammation, Neuroscience, Others

1638152

0.9983

C20H24N10O10P2S2

690.54

O[C@H]1[C@]2([H])[C@H](N3C4=NC=NC(N)=C4N=C3)OC1([H])CO[P@@](O[C@]5([H])[C@@](O[C@@H](N6C7=NC=NC(N)=C7N=C6)[C@@H]5O)([H])CO[P@](O2)(S)=O)(S)=O

-20°C

Ice Packs

Small Compound