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Molfinity

Aflatrem - CAS 70553-75-2

Aflatrem - CAS 70553-75-2

SKU:MF-0064803

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  • Bioactivity

    Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems. Aflatrem potentiates the gamma-aminobutyric acid (GABA) -induced chloride current, the potentiating action of aflatrem on the GABAA receptor channel may explain the initial symptoms of intoxication caused by aflatrem in vivo.

  • Target

    GABA Receptor

  • Related Pathways

    Membrane transporter/Ion channel, Neuroscience

  • CAS Number

    70476

  • Molecular Formula

    C32H39NO4

  • Molecular Weight

    501.667

  • SMILES

    CC(C)(C=C)c1cccc2[nH]c3c(CC4CCC5(O)C6=CC(=O)C7OC6(CCC5(C)C34C)OC7(C)C)c12 |t:19|

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product