Molfinity

AFP464 free base - CAS 468719-52-0

SKU:MF-0004333-01

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Product Details

Bioactivity
AFP464 (NSC710464) free base is an active HIF-1α inhibitor (IC50: 0.25 μM) and a potent aryl hydrocarbon receptor (AhR) activator.
Target
HIF/HIF Prolyl-Hydroxylase, HIF
Related Pathways
Metabolism, Angiogenesis, Chromatin/Epigenetic
CAS Number
468667
Molecular Formula
C22H23F3N4O3
Molecular Weight
448.44
SMILES
FC1=C2C(C(=O)C=C(O2)C3=CC(F)=C(NC([C@H](CCCCN)N)=O)C=C3)=C(N)C(F)=C1C
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound