AG-13958 monohydrochloride - CAS 319463-49-5

AG-13958 monohydrochloride is the HCl salt of AG-13958 --- a VEGFA inhibitor potentially for the treatment of age-related macular degeneration. Neovascular AMD, a subtype characterized by the growth of new, pathologic blood vessels, results in most of the cases of severe and rapid vision loss associated with AMD. A critical activator of angiogenesis in neovascular AMD is VEGF.

Others, VEGFR

Tyrosine Kinase/Adaptors, Others, Angiogenesis

319409

C26H23ClFN7O

503.96

C(=C/C1=CC=CC=N1)\C=2C=3C(=CC(NC4=CC(NC(=O)C=5N(C)N=C(C)C5)=C(F)C=C4)=CC3)NN2.Cl

-20°C

Ice Packs

Small Compound