AG-825 - CAS 149092-50-2

AG-825 (Tyrphostin C15) is a selective and competitive ErbB2 inhibitor that inhibits tyrosine phosphorylation with an IC50 value of 0.35 μM.AG-825 (Tyrphostin C15) inhibits HER2 and shows anticancer activity in a mouse xenograft model of breast cancer.AG-825 (Tyrphostin C15) is a potentially active molecule for overcoming manganese-induced neurotoxicity or the development of Alzheimer's disease, and promotes apoptosis in human neutrophils, which could be used in the study of breast cancer.

Apoptosis, EGFR, Adrenergic Receptor

Neuroscience, Apoptosis, JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, GPCR/G Protein

149040

0.9952

C19H15N3O3S2

397.47

COc1cc(\C=C(/C#N)C(N)=O)cc(CSc2nc3ccccc3s2)c1O

-20°C

Ice Packs

Small Compound