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Molfinity

AG490 - CAS 133550-30-8

AG490 - CAS 133550-30-8

MF-0015399-01

$42.14 USD
$42.14 USD
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Product Details

  • Bioactivity

    AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50: 0.1 μM) . It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src.

  • Target

    JAK, STAT, Autophagy, EGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Autophagy, Angiogenesis, Stem Cells, JAK/STAT signaling, Chromatin/Epigenetic

  • CAS Number

    133512

  • Purity

    0.9985

  • Molecular Formula

    C17H14N2O3

  • Molecular Weight

    294.3

  • SMILES

    C(=C(/C(NCC1=CC=CC=C1)=O)\C#N)\C2=CC(O)=C(O)C=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound