(-) -Agelastatin A - CAS 152406-28-5

(-) -Agelastatin A is a member of the pyrrole-aminoimidazole marine alkaloid (PAI) family, capable of inhibiting β-catenin, GSK-3β, and osteopontin (OPN), exhibiting antiproliferative activity against various cancers such as leukaemia and breast cancer, and possessing a certain ability to penetrate the central nervous system (CNS) .

GSK-3, Apoptosis, Wnt/beta-catenin

PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Apoptosis, Stem Cells

152406-28-5

>99.99%

C12H13BrN4O3

341.16

BrC=1N2[C@]3([C@]([C@]4([C@@](O)(C3)N(C)C(=O)N4)[H])(NC(=O)C2=CC1)[H])[H]

-20°C

Ice Packs

Natural Product