AGN 205327 - CAS 2070018-29-8

AGN 205327 is a potent synthetic agonist of retinoic acid receptors (RARs), with EC50 values of 3766 nM for RARα, 734 nM for RARβ, and 32 nM for RARγ, and AGN 205327 demonstrates no inhibitory activity against retinoid X receptors (RXRs), thereby exhibiting selective receptor subtype targeting that makes AGN 205327 an important tool for probing retinoid signaling pathways and investigating therapeutic applications of RAR activation.

Autophagy, Retinoid Receptor

Autophagy, Metabolism

2069981

0.9971

C24H26N2O3

390.47

CC1(C)C=2C(=CC=C(C(=NO)C3=CC=4C(N3)=CC=C(C(O)=O)C4)C2)C(C)(C)CC1

-20°C

Ice Packs

Small Compound