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Molfinity

Agnuside - CAS 11027-63-7

Agnuside - CAS 11027-63-7

SKU:MF-0018169-01

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  • Bioactivity

    Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, and 82.1% of P-glycoprotein (P-gp) ATPase activity at concentrations of 5, 25, and 100 μM, respectively.

  • Target

    P-gp, Caspase, HIF/HIF Prolyl-Hydroxylase, ASCT, COX, Prostaglandin Receptor, NO Synthase

  • Related Pathways

    Chromatin/Epigenetic, Proteases/Proteasome, Apoptosis, Neuroscience, Membrane transporter/Ion channel, Immunology/Inflammation, GPCR/G Protein, Metabolism

  • CAS Number

    10957

  • Purity

    0.9981

  • Molecular Formula

    C22H26O11

  • Molecular Weight

    466.44

  • SMILES

    OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)C=C(COC(=O)c4ccc(O)cc4)[C@@H]23)[C@H](O)[C@@H](O)[C@@H]1O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product