Agomelatine hydrochloride - CAS 1176316-99-6

Agomelatine hydrochloride (S-20098 hydrochloride) is a specific MT1 and MT2 receptor agonist with Ki values of 0.1 nM for CHO-hMT1, 0.06 nM for HEK-hMT1, 0.12 nM for CHO-hMT2, and 0.27 nM for HEK-hMT2, respectively [1]. Additionally, Agomelatine hydrochloride is a selective antagonist of the 5-HT2C receptor with pKi values of 6.4 and 6.2 for native (porcine) and cloned human 5-HT2C receptors, respectively [2].

Endogenous Metabolite, 5-HT Receptor, Melatonin Receptor, MT Receptor

GPCR/G Protein, Metabolism, Neuroscience

1176211

>99.99%

C15H18ClNO2

279.76

Cl.COc1ccc2cccc(CCNC(C)=O)c2c1

-20°C

Ice Packs

Small Compound