Agomelatine (L (+) -Tartaric acid) - CAS 824393-18-2

Agomelatine (L (+) -Tartaric acid) is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2), and Agomelatine (S-20098) . L (+) -Tartaric acid also functions as a selective 5-HT2C receptor antagonist (pKis: 6.4 and 6.2 at native porcine and cloned human 5-HT2C receptors), actively supporting research into melatonergic signaling pathways, receptor-mediated regulation, and novel psychiatric therapeutics by enabling precise modulation of circadian and serotonergic systems in cellular models to improve neuropharmacological understanding and experimental reproducibility across neuroscientific and clinical translational studies.

MT Receptor, 5-HT Receptor

GPCR/G Protein, Neuroscience

824373

0.9979

C19H23NO8

393.39

[C@@H]([C@H](C(O)=O)O)(C(O)=O)O.C(CNC(C)=O)C=1C2=C(C=CC(OC)=C2)C=CC1

-20°C

Ice Packs

Small Compound