AH22921 - CAS 74480-23-2

AH22921 is an EP4 prostaglandin receptor antagonist with the ability to antagonize the activation of adenylyl cyclase by prostaglandins in CHO cells. It induces a rightward shift in the PGE? concentration-response curve in these cells, functioning as a non-competitive antagonist. AH22921 is selective for the EP4 receptor, inhibiting its activity in CHO cells without affecting the PGE? concentration-response curve in NPE cells that contain the EP2 receptor.

Prostaglandin Receptor, Others

GPCR/G Protein, Immunology/Inflammation, Others

74455

C29H35NO5

477.59

C(/C=C\CCCC(O)=O)[C@H]1[C@@H](C(=O)C[C@H]1OCC2=CC=C(C=C2)C3=CC=CC=C3)N4CCOCC4

-20°C

Ice Packs

Small Compound