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AK301 - CAS 314022-97-4
AK301 - CAS 314022-97-4
SKU:MF-0062367-01
Regular price
$234.28 USD
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$234.28 USD
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Product Details
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Bioactivity
AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM) . Colon cancer cells arrested in mitosis with AK301 readily underwent a p53-dependent apoptosis following compound withdrawal and arrest release.
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Target
Apoptosis, Microtubule Associated
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Related Pathways
Apoptosis, Cytoskeletal Signaling
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CAS Number
313921
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Purity
0.9975
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Molecular Formula
C19H21ClN2O2
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Molecular Weight
344.84
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SMILES
C(=O)(C1=C(OCC)C=CC=C1)N2CCN(CC2)C3=CC(Cl)=CC=C3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound