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Molfinity

AK301 - CAS 314022-97-4

AK301 - CAS 314022-97-4

SKU:MF-0062367-01

Regular price $234.28 USD
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  • Bioactivity

    AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM) . Colon cancer cells arrested in mitosis with AK301 readily underwent a p53-dependent apoptosis following compound withdrawal and arrest release.

  • Target

    Apoptosis, Microtubule Associated

  • Related Pathways

    Apoptosis, Cytoskeletal Signaling

  • CAS Number

    313921

  • Purity

    0.9975

  • Molecular Formula

    C19H21ClN2O2

  • Molecular Weight

    344.84

  • SMILES

    C(=O)(C1=C(OCC)C=CC=C1)N2CCN(CC2)C3=CC(Cl)=CC=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound