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AKI603 - CAS 1432515-73-5

AKI603 - CAS 1432515-73-5

SKU:MF-0062378-01

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  • Bioactivity

    AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA) (IC50 = 12.3 nM) . AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2].

  • Target

    Aurora Kinase

  • Related Pathways

    Cell Cycle/Checkpoint, Chromatin/Epigenetic

  • CAS Number

    1432437

  • Purity

    0.9981

  • Molecular Formula

    C19H23N9O2

  • Molecular Weight

    409.45

  • SMILES

    CN1CCN(CC1)c1cc(Nc2cc(C)[nH]n2)nc(Nc2ccc(cc2)[N+]([O-])=O)n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound