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AKI603 - CAS 1432515-73-5
AKI603 - CAS 1432515-73-5
SKU:MF-0062378-01
Regular price
$54.85 USD
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$54.85 USD
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Product Details
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Bioactivity
AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA) (IC50 = 12.3 nM) . AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2].
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Target
Aurora Kinase
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Related Pathways
Cell Cycle/Checkpoint, Chromatin/Epigenetic
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CAS Number
1432437
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Purity
0.9981
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Molecular Formula
C19H23N9O2
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Molecular Weight
409.45
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SMILES
CN1CCN(CC1)c1cc(Nc2cc(C)[nH]n2)nc(Nc2ccc(cc2)[N+]([O-])=O)n1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound