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AKR1C3-IN-12 - CAS 891075-67-5

AKR1C3-IN-12 - CAS 891075-67-5

SKU:MF-0062399-01

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  • Bioactivity

    AKR1C3-IN-12 (compound 2j), an inhibitor of aldo-keto reductase 1C3 (AKR1C3), exhibits potent activity with an IC50 of 27 nM. It has been shown to enhance the effectiveness of Gemcitabine and Cisplatin in treating bladder cancer [1].

  • Target

    Reductase

  • Related Pathways

    Metabolism, Endocrinology/Hormones

  • CAS Number

    891075-67-5

  • Molecular Formula

    C17H14N2O3

  • Molecular Weight

    294.3

  • SMILES

    O=C(NC1=CC=C(C=C1)C)C2=CC=3C=CC=C(O)C3OC2=N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound