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AKR1C3-IN-12 - CAS 891075-67-5
AKR1C3-IN-12 - CAS 891075-67-5
SKU:MF-0062399-01
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$1,383.80 USD
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Product Details
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Bioactivity
AKR1C3-IN-12 (compound 2j), an inhibitor of aldo-keto reductase 1C3 (AKR1C3), exhibits potent activity with an IC50 of 27 nM. It has been shown to enhance the effectiveness of Gemcitabine and Cisplatin in treating bladder cancer [1].
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Target
Reductase
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Related Pathways
Metabolism, Endocrinology/Hormones
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CAS Number
891075-67-5
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Molecular Formula
C17H14N2O3
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Molecular Weight
294.3
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SMILES
O=C(NC1=CC=C(C=C1)C)C2=CC=3C=CC=C(O)C3OC2=N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound