Akt1&PKA-IN-1 - CAS 1334107-58-2

Akt1&PKA-IN-1 is a potent dual inhibitor of Akt and PKA, with IC50 values of 0.11 μM for Akt, 0.03 μM for PKAα, and 9.8 μM for CDK2, demonstrating selective inhibition of cyclin-dependent kinase 2 (CDK2) .

Akt, PKA, Others, CDK

Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Others

1334047

C20H17Cl2N3O

386.27

[C@@H](NC(=O)C1=CC2=C(C=C1)C=NC=C2)(C3=CC(Cl)=C(Cl)C=C3)C4CNC4

-20°C

Ice Packs

Small Compound