Akuammigine - CAS 642-17-1

Akuammigine has in vitro antimalarial activity. Akuammigine competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptors, yielding pA2 values of 4.68. Akuammidine also shows a preference for mu-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 microM at mu-, delta- and kappa-opioid binding sites, respectively.

Adrenergic Receptor, Opioid Receptor

Endocrinology/Hormones, Neuroscience, GPCR/G Protein

624

C21H24N2O3

352.43

COC(=O)C1=CO[C@@H](C)[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@H]3C[C@H]12

-20°C

Ice Packs

Natural Product