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Molfinity

AL 8697 - CAS 1057394-06-5

AL 8697 - CAS 1057394-06-5

MF-0004354-01

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Product Details

  • Bioactivity

    AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases. AL 8697 has anti-inflammatory activity.

  • Target

    P38 MAPK, Autophagy

  • Related Pathways

    MAPK, Autophagy

  • CAS Number

    1057394-06-5

  • Purity

    0.9989

  • Molecular Formula

    C21H21F3N4O

  • Molecular Weight

    402.41

  • SMILES

    Cc1c(F)cc(cc1-c1c(F)cn2c(nnc2c1F)C(C)(C)C)C(=O)NC1CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound