Alisertib Sodium - CAS 1028486-06-7

Alisertib Sodium (MLN 8237 Sodium) is a selective Aurora A inhibitor that causes G2/M phase arrest and chromosomal misalignment, leading to tumour cell apoptosis, and can also inhibit STAT3 Tyr705 phosphorylation, resulting in downregulation of c-Myc expression.

Others, Apoptosis, Aurora Kinase, Autophagy, STAT

Autophagy, Chromatin/Epigenetic, Others, Apoptosis, Cell Cycle/Checkpoint, Stem Cells, JAK/STAT signaling

1028486-06-7

0.9977

C27H19ClFN4NaO4

540.91

O=C(C1=CC=C(NC2=NC(C3=C(C(C4=C(OC)C=CC=C4F)=NC5)C=C(Cl)C=C3)=C5C=N2)C=C1OC)[O-].[Na+]

-20°C

Ice Packs

Inhibitors & Agonists