Alisol B acetate - CAS 19865-76-0

Alisol B acetate can induce Bax nuclear translocation and apoptosis in human hormone-resistant prostate cancer PC-3 cells, the Bax activation and translocation from the cytosol to nucleus might be a crucial response to the apoptotic effect. Alisol B acetate exhibits an antiproliferative effect in SGC7901 cells by inducing apoptosis, apoptosis of SGC7901 cells involves mitochondria-caspase and PI3K/Akt dependent pathways.

Caspase, Apoptosis, Akt, PI3K

Proteases/Proteasome, Cytoskeletal Signaling, Apoptosis, PI3K/Akt/mTOR signaling

19789

C32H50O5

514.74

CC(C)C(=O)[C@H](C[C@@H](C)C1=C2C[C@H](O)[C@H]3[C@@]4(C)CCC(=O)C(C)(C)[C@@H]4CC[C@]3(C)[C@@]2(C)CC1)OC(C)=O

-20°C

Ice Packs

Natural Product