ALK/EGFR-IN-2 - CAS 2730432-75-2

ALK/EGFR-IN-2 is a potent dual inhibitor targeting ALK and EGFR, promoting apoptosis and G0/G1 cell cycle arrest in cancer cells. It effectively suppresses proliferation in H1975, PC9, and Baf3-EML4-ALK cancer cell lines, with IC50s of 0.0034, 0.0065, and 0.0018 μM, respectively [1].

ALK, Others

Others, Tyrosine Kinase/Adaptors, Angiogenesis

2730355

C27H34ClN7O3S

572.12

N(CCN(C)C)(C)C1=C(NC(C=C)=O)C=C(NC=2N=C(NC3=C(S(CC)=O)C=CC=C3)C(Cl)=CN2)C(OC)=C1

-20°C

Ice Packs

Small Compound