ALK-IN-22 - CAS 2468219-09-0

ALK-IN-22 (compound I-24) is a potent ALK inhibitor with an IC50 of 2.3 nM for ALK, 3.7 nM for ALKL1196M, and 2.9 nM for ALKG1202R. It down-regulates phosphorylation of ALK and its downstream proteins, inducing apoptosis. ALK-IN-22 is suitable for studying tumors.

Others, Apoptosis, ALK

Angiogenesis, Others, Tyrosine Kinase/Adaptors, Apoptosis

2468219-09-0

C24H24ClN7O2

477.95

C(N(C)C)(=O)C=1C=2C(=CC(NC=3N=C(NC4=C(C(NC)=O)C=CC=C4)C(Cl)=CN3)=CC2)NC1C

-20°C

Ice Packs

Small Compound