Molfinity

ALK/ROS1-IN-1 - CAS 2365497-07-8

SKU:MF-0004364-01

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Product Details

Bioactivity
ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor (IC50s: 0.530 μM and 0.174 μM for ROS1 and ALK enzyme) .
Target
ROS Kinase, ALK, Others
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Others
CAS Number
2365497-07-8
Molecular Formula
C30H35F3N6O3
Molecular Weight
584.63
SMILES
N(C1=CC(=CC=N1)N2C[C@@H](C(NCC3=CC=C(OC(F)(F)F)C=C3)=O)CCC2)C4=C(OC)C=C(C=C4)N5CCNCC5
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound