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ALK5-IN-28 - CAS 2785430-84-2
ALK5-IN-28 - CAS 2785430-84-2
SKU:MF-0062554-01
Regular price
$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
ALK5-IN-28 is a selective inhibitor of ALK-5 with an IC50 ≤ 10 nM that inhibits TGF-β-induced SMAD signalling.ALK5-IN-28 has the potential to inhibit tumour growth in vivo.ALK5-IN-28 can be used to study proliferative diseases (e.g. cancer, fibrotic diseases, systemic sclerosis) .
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Target
Others, TGF-beta/Smad
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Related Pathways
Stem Cells, Others
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CAS Number
2785344
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Molecular Formula
C25H27N7
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Molecular Weight
425.53
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SMILES
N(C=1C2=C(C(C)=CC=C2)N=NC1)C3=NC(NC4=CC=C(CC5CCNCC5)C=C4)=NC=C3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound