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ALK5-IN-79 - CAS 2725056-38-0

ALK5-IN-79 - CAS 2725056-38-0

SKU:MF-0062556-01

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  • Bioactivity

    ALK5-IN-79 (compound 57), an ALK inhibitor, exhibits anticancer activity by inhibiting the TGF-β1/SMAD signaling pathway. It effectively reduces the production of extracellular matrix (ECM) and collagen deposition. Moreover, ALK5-IN-79 demonstrates satisfactory pharmacokinetic (PK) properties and favorable in vivo tolerance.

  • Target

    ALK

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    2725056-38-0

  • Molecular Formula

    C23H27N7O

  • Molecular Weight

    417.51

  • SMILES

    O=C(N1CCC(CCN2N=C(C3=CC=C4NC=C(C4=C3)C)C=5C(=NC=NC52)N)CC1)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound