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ALK5-IN-79 - CAS 2725056-38-0
ALK5-IN-79 - CAS 2725056-38-0
SKU:MF-0062556-01
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$1,647.05 USD
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$1,647.05 USD
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Product Details
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Bioactivity
ALK5-IN-79 (compound 57), an ALK inhibitor, exhibits anticancer activity by inhibiting the TGF-β1/SMAD signaling pathway. It effectively reduces the production of extracellular matrix (ECM) and collagen deposition. Moreover, ALK5-IN-79 demonstrates satisfactory pharmacokinetic (PK) properties and favorable in vivo tolerance.
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Target
ALK
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Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
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CAS Number
2725056-38-0
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Molecular Formula
C23H27N7O
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Molecular Weight
417.51
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SMILES
O=C(N1CCC(CCN2N=C(C3=CC=C4NC=C(C4=C3)C)C=5C(=NC=NC52)N)CC1)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound