ALK5-IN-8 - CAS 2705900-81-6

ALK5-IN-8 is a highly effective inhibitor of TGFβRI (ALK5) . It hinders the phosphorylation of ALK5 on downstream signaling proteins (Smad2 or Smad3) by obstructing the interaction between TGFβRI and ligands. Consequently, it disrupts or prevents TGF-β signaling. ALK5-IN-8 shows promise in the study of diverse diseases associated with ALK5-mediated pathways[1].

Others, TGF-beta/Smad

Others, Stem Cells

2705813

C19H15FN4O2

350.35

C(OCC)(=O)C1=C2N(N=C1)C=CC(=C2)C=3C(=NNC3)C4=CC=C(F)C=C4

-20°C

Ice Packs

Small Compound