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Aloc-D-Ala-Phe-Lys (Aloc) -PAB-PNP - CAS 253863-34-2
Aloc-D-Ala-Phe-Lys (Aloc) -PAB-PNP - CAS 253863-34-2
SKU:MF-0034417-01
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Product Details
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Bioactivity
Aloc-D-Ala-Phe-Lys (Aloc) -PAB-PNP is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs), innovative therapeutic agents that combine the targeting ability of antibodies with potent cytotoxic drugs.
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Target
ADC Linker
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Related Pathways
Antibody-drug Conjugate/ADC Related
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CAS Number
253827
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Molecular Formula
C40H46N6O12
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Molecular Weight
802.838
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SMILES
C[C@@H](NC(=O)OCC=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)OCC=C)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)N(=O)=O)cc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC