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Molfinity

Alofanib - CAS 1612888-66-0

Alofanib - CAS 1612888-66-0

MF-0013405-01

$33.17 USD
$33.17 USD
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Product Details

  • Bioactivity

    Alofanib (RPT835) is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM) . It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding.

  • Target

    Apoptosis, FGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Apoptosis, Angiogenesis

  • CAS Number

    1612822

  • Purity

    0.9981

  • Molecular Formula

    C19H15N3O6S

  • Molecular Weight

    413.4

  • SMILES

    Cc1cc(c(NS(=O)(=O)c2cccc(c2)C(O)=O)cc1-c1cccnc1)[N+]([O-])=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound