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Alpelisib - CAS 1217486-61-7

Alpelisib - CAS 1217486-61-7

MF-0065300-01

$34.67 USD
$34.67 USD
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Product Details

  • Bioactivity

    Alpelisib (BYL-719) is a PI3Kα inhibitor (IC50=5 nM) with selective, potent, and oral activity, inhibiting PI3Kβ/γ/δ with low activity (IC50=250/290/1200 nM) . Alpelisib demonstrates antitumor activity and specifically targets PIK3CA mutant tumors.

  • Target

    PI3K

  • Related Pathways

    PI3K/Akt/mTOR signaling

  • CAS Number

    1217418

  • Purity

    0.9973

  • Molecular Formula

    C19H22F3N5O2S

  • Molecular Weight

    441.47

  • SMILES

    Cc1nc(NC(=O)N2CCC[C@H]2C(N)=O)sc1-c1ccnc(c1)C(C)(C)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound