ALR-27 - CAS 903639-13-4

ALR-27 serves as an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and exhibits anti-inflammatory properties. It effectively inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM without significantly inhibiting 5-LOX directly. Additionally, ALR-27 decreases prostaglandin and leukotriene (LT) production in neutrophils and enhances the production of specialized prolytic mediators in certain human macrophage phenotypes [1].

FLAP

Immunology/Inflammation

903639-13-4

C19H22O3

298.38

C(CC1=CC=C(O)C=C1)C2CCC(CO2)C3=CC=C(O)C=C3

-20°C

Ice Packs

Small Compound