ALT-007 - CAS 2035010-37-6

ALT-007 is an orally bioavailable inhibitor of serine palmitoyltransferase (SPT), the rate-limiting enzyme in de novo ceramide synthesis. In murine models of age-related sarcopenia, ALT-007 effectively restores muscle mass and function impaired by aging. Additionally, ALT-007 may enhance protein homeostasis in Caenorhabditis elegans and in mouse models of aging and age-associated diseases, acting as a ceramide inhibitor.

Acyltransferase

Metabolism

2034967

C25H26F3N5O5

533.5

O=C(NC1C2=C(C=NN2C(C)C)N(C(=O)C3=CN=C(OC)C(OC)=C3)CC1)C=4C=CC=CC4OC(F)(F)F

-20°C

Ice Packs

Small Compound