Alvimopan dihydrate (LY246736 dihydrate) - CAS 170098-38-1

Alvimopan dihydrate (ADL 8-2698 dihydrate) is a potent, selective, orally active, and reversible μ-opioid receptor antagonist with an IC50 of 1.7 nM. Highly selective for the μ-opioid receptor (Ki = 0.47 nM) over κ- and δ-opioid receptors (Kis = 100 and 12 nM, respectively), Alvimopan dihydrate can be used for research on postoperative ileus [1] [2] [3].

Opioid Receptor, Others

Others, GPCR/G Protein, Endocrinology/Hormones, Neuroscience

170059

C25H36N2O6

460.56

O.O.C[C@H]1CN(C[C@H](Cc2ccccc2)C(=O)NCC(O)=O)CC[C@@]1(C)c1cccc(O)c1

-20°C

Ice Packs

Small Compound