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Molfinity

AM-4668 - CAS 1011531-27-3

AM-4668 - CAS 1011531-27-3

SKU:MF-0031982-01

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  • Bioactivity

    AM-4668, a GPR40 (FFA1) agonist with oral availability, was optimized to reduce central nervous system (CNS) permeability, with a mouse brain/plasma ratio of only 0.02, and significantly reduced blood glucose levels in human GPR40 knock-in mice.

  • Target

    GPCR

  • Related Pathways

    GPCR/G Protein, Endocrinology/Hormones

  • CAS Number

    1011501

  • Purity

    0.9992

  • Molecular Formula

    C24H19F3N2O4S

  • Molecular Weight

    488.48

  • SMILES

    C(OC1=CC=C([C@H](CC(O)=O)C=2C=CON2)C=C1)C=3SC(=NC3C)C4=CC=C(C(F)(F)F)C=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound