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Molfinity
AM-6761 - CAS 1584732-36-4
AM-6761 - CAS 1584732-36-4
SKU:MF-0052392-01
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Product Details
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Bioactivity
AM-6761 is a potent inhibitor of the MDM2-p53 interaction. In the SJSA-1 osteosarcoma xenograft model, AM-6761 shows excellent antitumor activity with an ED50 of 11 mg/kg.
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Target
Others
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Related Pathways
Others
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CAS Number
1584692
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Molecular Formula
C33H37Cl2FN2O5S2
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Molecular Weight
695.69
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SMILES
[C@H](CS(C(C)(C)C)(=O)=O)(N1[C@@H]([C@H](C[C@@](CC=2SC(CC(O)=O)=CN2)(C)C1=O)C3=CC(Cl)=CC=C3)C4=CC(F)=C(Cl)C=C4)[C@@H]5CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound