AM-9514 - CAS 1442677-18-0

AM-9514 is a novel, potent Glucokinase (GK) activator. AM-9514 showed a favorable combination of in vitro potency, enzyme kinetic properties, acceptable pharmacokinetic profiles in preclinical species, and robust efficacy in a rodent PD model. Glucokinase (GK) activators represent a class of type 2 diabetes therapeutics actively pursued due to the central role that GK plays in regulating glucose homeostasis.

Others

Others

1442659

C18H25N5O4

375.42

O(C1=C(NC(NC)=O)N=CC([C@@H](O)[C@]2(C[C@](C)(O)C2)[H])=C1)C=3N(CC)N=CC3

-20°C

Ice Packs

Small Compound