AM-9635 - CAS 1338483-10-5

AM-9635 is a potent and selective PI3Kδ inhibitor. AM-9635 showes good cellular potency (in vitro pAKT IC50 = 4.2 nM) . AM-96352 inhibits KLH-specific IgG and IgM in a dosedependent manner AM-9635 is well tolerated at all doses and exhibits significantly reduced IgG and IgM specific antibodies . PI3Kα and PI3Kβ are ubiquitously expressed and play a role in cell growth, division, and survival.

Others, PI3K, Akt

Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Others

1338468

C19H14F2N8

392.36

[C@H](NC=1C(C#N)=C(N)N=CN1)(C)C=2N(C=3C(N2)=CC=C(F)C3)C=4C=C(F)C=NC4

-20°C

Ice Packs

Small Compound