AM404 - CAS 183718-77-6

AM404 is an endocannabinoid reuptake inhibitor, a TRPV (1) activator, a paracetamol metabolite, with neuroprotective and anticancer activity that blocks anandamide transport. AM404 inhibits NFAT and NF-kappaB signaling pathways and impairs migration and invasiveness of neuroblastoma cells, preventing prostaglandin synthesis in activated microglia by inhibiting COX activity.

Others, Cannabinoid Receptor, TRP/TRPV Channel

Membrane transporter/Ion channel, GPCR/G Protein, Others

183635

C26H37NO2

395.58

N(C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)C1=CC=C(O)C=C1

-20°C

Ice Packs

Small Compound