AM432 sodium - CAS 1263409-34-2

AM432 (sodium) is a potent and selective DP2 receptor (CRTH2) antagonist. It demonstrates excellent efficacy in a long-term incubation assay involving shape change in human whole blood eosinophils. Additionally, AM432 (sodium) exhibits outstanding pharmacokinetics in inflammation models in both dogs and mice.

Prostaglandin Receptor

Immunology/Inflammation, GPCR/G Protein

1263373

C29H31N2NaO5

510.56

O=C(CC1=CC=C(C(C2=CC=C(C3=CC=C(OCC)N=C3)C=C2CN(CC)C(C4CC4)=O)=C1)OC)[O-].[Na+]

-20°C

Ice Packs

Small Compound