γ-Amanitin - CAS 21150-23-2

γ-Amanitin, an ADC (antibody-drug conjugate) cytotoxin isolated from mushrooms, inhibits RNA polymerase II, disrupting mRNA synthesis. It exhibits effects akin to those of α-Amanitin and β-Amanitin.

ADC Cytotoxin, DNA/RNA Synthesis

Cell Cycle/Checkpoint, Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair

21125

C39H54N10O13S

902.98

CCC(C)C1NC(=O)CNC(=O)C2Cc3c([nH]c4cc(O)ccc34)S(=O)CC(NC(=O)CNC1=O)C(=O)NC(CC(N)=O)C(=O)N1CC(O)CC1C(=O)NC(C(C)C(C)O)C(=O)N2

-20°C

Ice Packs

Natural Product