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β-Amanitin - CAS 21150-22-1
β-Amanitin - CAS 21150-22-1
SKU:MF-0031460
Regular price
$1,190.75 USD
Regular price
Sale price
$1,190.75 USD
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Product Details
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Bioactivity
β-Amanitin, a cyclic peptide toxin found in the poisonous Amanita phalloides mushroom, inhibits eukaryotic RNA polymerase II and III, thereby disrupting protein synthesis.
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Target
DNA/RNA Synthesis, ADC Cytotoxin
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Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Antibody-drug Conjugate/ADC Related
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CAS Number
21127
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Molecular Formula
C39H53N9O15S
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Molecular Weight
919.96
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SMILES
[H][C@@]12C[C@@H](O)CN1C(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]1([H])C[S@](=O)c3[nH]c4cc(O)ccc4c3C[C@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@@H](C)[C@@H](O)CO)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)NCC(=O)N1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound